This study investigates a topical facial test formulation containing hexylresorcinol, silymarin, 20% vitamin C, and 5% vitamin E in a proprietary anhydrous vehicle by clinical means as well as in skin explants for UVB photoprotective effects. The clinical study was conducted on 42 female subjects who were evaluated by a dermatologist investigator for brightening, evenness, fine lines, wrinkles, and global appearance. The results show the test formulation was effective clinically in showing skin brightness improvement and also effective in decreasing UVB-induced photodamage in skin explants.
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