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PCA Skin Certified Professionals
Patients showed a reduction in fine lines, wrinkles, firming of the skin and an evening of skin tone.

intensive brightening treatment: 0.5% pure retinol night

Smooth the skin’s surface and deliver allover brightening

0.5% pure retinol, niacinamide and hexylresorcinol are carried deep into the skin through a patented OmniSome delivery system, while additional actives smooth the skin’s surface and deliver allover brightening.

Application of retinol to human skin has been shown to induce epidermal thickening and cellular retinoid binding proteins characteristic of retinoic acid; this evidence supports the hypothesis that retinol acts as a prohormone of retinoic acid, but without significant levels of irritation.1 The changes in skin treated with retinol are similar to those produced by retinoic acid, but without measurable irritation. These changes include stimulation of fibroblast growth, reduction of MMP levels, stimulation of collagen synthesis2 and anti-melanogenic activity.3

Clinical information
In a study completed with five patients using the product with basic support products over a 10-week period, the investigating clinician reported 100% of patients showed positive changes in their skin with 80% of patients showing significant improvement in skin discoloration. All patients showed a reduction in fine lines, wrinkles, firming of the skin and an evening of skin tone.



Conclusion
Studies demonstrate that Intensive Brightening Treatment: 0.5% pure retinol night provides visible improvement in skin discoloration, fines lines, wrinkles, texture and the overall radiance of the skin. All patients showed positive improvement in their skin and experienced moderate dryness for no more than a two week period. No other adverse events were noted.

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